| Río Grande Department | |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | 180px |
| Pushpin Map Caption: | Location of Río Grande Department within Tierra del Fuego Province |
| Coordinates: | -53.7864°N -67.6967°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Tierra del Fuego Province |
| Seat Type: | Head town |
| Seat: | Río Grande |
| Unit Pref: | Metric |
| Area Footnotes: | [1] |
| Area Total Km2: | 12181 |
| Population Total: | 70042 |
| Population As Of: | 2010 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
Río Grande Department (Spanish; Castilian: Departamento Río Grande) is a department of Argentina in Tierra del Fuego Province, Argentina. The capital city of the department is situated in Río Grande.