| Río Cuarto Department | |
| Native Name: | Departamento Río Cuarto |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | frameless |
| Coordinates: | -33.1333°N -84°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Established Title: | Foundation |
| Established Date: | 23 July 1888 |
| Founder: | provincial law |
| Seat Type: | Capital |
| Seat: | Río Cuarto |
| Unit Pref: | Metric |
| Area Total Km2: | 18394 |
| Population Footnotes: | [1] |
| Population Total: | 292293 |
| Population Density Km2: | auto |
| Population Blank1 Title: | Pop. change |
| Population Blank1: | +18.16% |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | Postal code |
| Postal Code: | X5800 |
| Area Code Type: | Dialing code |
| Area Code: | 0358 |
| Blank Name Sec1: | Distances to |
| Blank Info Sec1: | |
| Blank1 Info Sec1: | 608km (378miles) |
| Blank2 Name Sec1: | Córdoba |
| Blank2 Info Sec1: | 235km (146miles) |
Río Cuarto Department is a department of Córdoba Province in Argentina. Its capital city is Río Cuarto, which is located around 608 km from Capital Federal.