| Río Blanco | |
| Settlement Type: | Municipality |
| Pushpin Map: | Nicaragua |
| Pushpin Label Position: | left |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Nicaragua |
| Subdivision Type: | Country |
| Subdivision Name: |  Nicaragua |
| Subdivision Type1: | Department |
| Subdivision Name1: | Matagalpa |
| Unit Pref: | Imperial |
| Area Total Km2: | 663 |
| Population As Of: | 2022 estimate |
| Population Footnotes: | [1] |
| Population Total: | 37197 |
| Population Density Km2: | auto |
| Population Urban: | 18232 |
| Coordinates: | 12.9333°N -98°W |
| Blank Name: | Climate |
| Blank Info: | Am |
Río Blanco is a town and a municipality in the Matagalpa Department of Nicaragua.