Quinfamide Explained

Quinfamide is a drug that has anti-parasitic properties.[1]

Synthesis

Quinfamide is one of a relatively small family of antiamoebic compounds containing a dichloroacetamide function.The synthesis begins by amidation of 6-hydroxytetrahydroquinoline with dichloroacetyl chloride. The sequence is completed by acylation with 2-furoyl chloride.

Notes and References

  1. Davila-Gutierrez CE, Vasquez C, Trujillo-Hernandez B, Huerta M . Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children . The American Journal of Tropical Medicine and Hygiene . 66 . 3 . 251–4 . March 2002 . 12139216 . 10.4269/ajtmh.2002.66.251 . free .

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