Qui-Lim Choo Explained

Qui-Lim Choo
Birth Place:Singapore
Fields:Virology
Workplaces:Chiron Corporation
Thesis Title:Neuronal proteins examined by a two-dimensional gel system
Thesis Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253923
Thesis Year:1980
Known For:Hepatitis C
Hepatitis D
Awards:Karl Landsteiner Memorial Award (1992)
William Beaumont Prize (1994)
Dale A. Smith Memorial Award (2005)

Qui-Lim Choo is a Singapore-born scientist, who along with Michael Houghton, George Kuo and Daniel W. Bradley, co-discovered and cloned Hepatitis C in 1989.[1] [2] He also co-discovered the Hepatitis D genome in 1986.[3] The discovery of Hepatitis C led to the rapid development of diagnostic reagents to detect Hepatitis C virus in blood supplies which has reduced the risk of acquiring hepatitis C through blood transfusion from one in three to about one in two million.[4] [5] It is estimated that antibody testing has prevented at least 40,000 new infections per year in the US alone and many more worldwide.[6]

Early life and education

Choo received his undergraduate training at Queen Elizabeth College in 1973 and completed his PhD in biochemistry at King's College London in 1980.[7] He trained under William J. Rutter at the University of California, San Francisco before joining Chiron Corporation.[7]

Awards and recognition

He was awarded the Karl Landsteiner Memorial Award (1992) and Dale A. Smith Memorial Award (2005) of the American Association of Blood Banks, and the William Beaumont Prize of the American Gastroenterological Association in 1994.[8] [9]

Notes and References

  1. Web site: Singapore-born scientist pioneers test. NewspaperSG. 4 October 2016.
  2. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M . Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome . Science . 244 . 4902 . 359–62 . April 1989 . 2523562 . 10.1126/science.2523562. 10.1.1.469.3592 .
  3. Wang. KS . Choo, QL . Weiner, AJ . Ou, JH . Najarian, RC . Thayer, RM . Mullenbach, GT . Denniston, KJ . Gerin, JL . Houghton, M . Michael Houghton (virologist) . Structure, sequence and expression of the hepatitis delta (delta) viral genome. Nature. 9 October 1986. 323. 6088. 508–14. 3762705. 10.1038/323508a0. 4265339 . free .
  4. Web site: Opinion: Nobel-worthy discovery right in our backyard. Canadian for Health Research. 4 September 2016.
  5. Web site: Science world abuzz as virologist turns down Gairdner award. The Globe and Mail. 10 September 2016.
  6. Book: Thompson. Gilbert. Pioneers of Medicine Without a Nobel Prize. 2014. 209. 9781783263868.
  7. Book: Liver Cirrhosis and Its Development - Google Books. 12 January 2014. 9780792387602. Boyer. J.L. Blum. H.E. Maier. K.P. Sauerbruch. T.. Stalder. G.A. 2001-03-31.
  8. Web site: List of Past AABB Award Recipients. AABB. 4 October 2016.
  9. Web site: William Beaumont Prize. American Gastroenterological Association. 4 October 2016.