| Province: | QC |
| Type: | QC |
| Route: | 385 |
| Maint: | Transports Québec |
| Map: | Route 385-QC.png |
| Length Km: | 84 |
| Length Round: | 1 |
| Length Ref: | [1] |
| Direction B: | North |
| Direction A: | South |
| Terminus B: | Labrieville |
| Terminus A: | in Forestville |
| Previous Type: | QC |
| Previous Route: | 382 |
| Next Type: | QC |
| Next Route: | 386 |
| Cities: | Forestville |
Route 385 is a provincial highway located in the Côte-Nord region in eastern Quebec. The highway runs from the junction of Route 138 in Forestville and ends over 80 kilometers further north into large wooded areas which the main purpose of the road is for the wood industry in the Côte-Nord region.