| Province: | QC |
| Type: | QC |
| Route: | 104 |
| Maint: | Transports Québec |
| Map: | Route 104-QC.png |
| Length Km: | 93.5 |
| Length Ref: | [1] |
| Length Round: | 1 |
| Direction A: | West |
| Direction B: | East |
| Terminus B: | in Lac-Brome (Knowlton) |
| History: | |
| Previous Type: | QC |
| Previous Route: | 101 |
| Next Type: | QC |
| Next Route: | 105 |
| Terminus A: | in La Prairie |
| Counties: | Roussillon / Le Haut-Richelieu / Brome-Missisquoi |
| Junction: | in La Prairie in Saint-Jean-sur-Richelieu in Cowansville in Lac-Brome |
Route 104 is an east/west highway on the south shore of the St. Lawrence River. Its eastern terminus is in Knowlton at the junction of Route 243 and its western terminus is in La Prairie at the junction of Route 134.