| Province: | QC |
| Type: | QC |
| Route: | 346 |
| Maint: | Transports Québec |
| Map: | Route 346-QC.png |
| Length Km: | 22.0 |
| Length Round: | 1 |
| Length Ref: | [1] |
| Direction B: | West |
| Direction A: | East |
| Terminus A: | in Saint-Charles-Borromée |
| Terminus B: | in Saint-Julienne |
| Previous Type: | QC |
| Previous Route: | 345 |
| Next Type: | QC |
| Next Route: | 347 |
| Counties: | Montcalm / Joliette |
| Junction: | in Saint-Liguori |
Route 346 is a provincial highway located in the Lanaudière region of Quebec, Canada. It runs from the junctions of Route 125 and Route 337 in Sainte-Julienne and ends at Route 343 in Saint-Charles-Borromée. The route also runs concurrent with Route 341 in Saint-Liguori.