Ethinylestradiol/levonorgestrel explained

Ethinylestradiol/levonorgestrel (EE/LNG) is a combined birth control pill made up of ethinylestradiol, an estrogen and levonorgestrel a progestin.[1] It is used for birth control, symptoms of menstruation, endometriosis, and as emergency contraception.[2] [1] It is taken by mouth.[2] Some preparations of EE/LNG additionally contain an iron supplement in the form of ferrous bisglycinate or ferrous fumarate.[3]

Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems.[1] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots.[1] However, it may be started immediately after a miscarriage or abortion.[4] Smoking while using combined birth control pills is not recommended.[2] It works by stopping ovulation, making the mucus at the opening to the cervix thick, and making the uterus not suitable for implantation.[2]

Ethinylestradiol/levonorgestrel has been approved for medical use in the United States since 1982.[2] It is on the World Health Organization's List of Essential Medicines.[5] It is available as a generic medication.[6] It is marketed under many brand names.[2] In 2021, it was the 144th most commonly prescribed medication in the United States, with more than 4million prescriptions.[7] [8]

See also

Notes and References

  1. Book: WHO Model Formulary 2008 . 2009 . 9789241547659 . ((World Health Organization)) . Stuart MC, Kouimtzi M, Hill SR . 10665/44053 . World Health Organization . World Health Organization . free . 363–5 .
  2. Web site: Ethinyl estradiol and levonorgestrel medical facts from Drugs.com. www.drugs.com. 1 January 2017. live. https://web.archive.org/web/20170101232357/https://www.drugs.com/mtm/ethinyl-estradiol-and-levonorgestrel.html. 1 January 2017.
  3. Book: Hamilton, RJ . Tarascon Pocket Pharmacopoeia 2020 Deluxe Lab-Coat Edition. April 2020. Jones & Bartlett Learning. 978-1-284-40304-6. 347–.
  4. Web site: Erlibelle 30micrograms/150micrograms film-coated tablets - Summary of Product Characteristics (SPC) - (eMC). www.medicines.org.uk. 1 January 2017. dead. https://web.archive.org/web/20170102081205/https://www.medicines.org.uk/emc/medicine/28986. 2 January 2017.
  5. Book: ((World Health Organization)) . World Health Organization model list of essential medicines: 21st list 2019 . 2019 . 10665/325771 . World Health Organization . World Health Organization . Geneva . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO .
  6. Book: Hamilton, RJ . Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. 2015. Jones & Bartlett Learning. 9781284057560. 349.
  7. Web site: The Top 300 of 2021 . ClinCalc . 14 January 2024 . 15 January 2024 . https://web.archive.org/web/20240115223848/https://clincalc.com/DrugStats/Top300Drugs.aspx . live .
  8. Web site: Ethinyl Estradiol; Levonorgestrel - Drug Usage Statistics . ClinCalc . 14 January 2024.