Pyxiloricaria menezesi is the only species of the monotypic genus Pyxiloricaria, a genus of the family Loricariidae of catfish (order Siluriformes).[1]
This species is endemic to Brazil where it occurs in the Paraguay River drainage.[1] P. menezesi inhabits sandy substrates and is sympatric with representatives of the genus Pseudohemiodon.[1]
Pyxiloricaria menezesi reaches a length of 14cm (06inches) SL. The phylogenetic position is uncertain; although it is thought to be closely related to Pseudohemiodon, it shares with Loricaria filamentous lips, inconspicuous fringed barbels on the lower lip, and shorter maxillary barbels.[1]