Pyrrolostatin Explained

Pyrrolostatin is a lipid peroxidation inhibitor with the molecular formula C₁₅H₂₁NO₂ which has been isolated from the bacterium Streptomyces chrestomyceticus.^[1]

Further reading

• Schmidt . Jens . Adrian . Juliane . Stark . Christian B. W. . Short and highly efficient synthesis of lipid peroxidation inhibitor pyrrolostatin and some analogues thereof . Organic & Biomolecular Chemistry . 22 July 2015 . 13 . 30 . 8173–8176 . 10.1039/C5OB01066G . 26154919 . en . 1477-0539.
• Dunford . Damian G. . Knight . David W. . A brief total synthesis of Pyrrolostatin . Tetrahedron Letters . 22 June 2016 . 57 . 25 . 2746–2748 . 10.1016/j.tetlet.2016.05.010 . en . 0040-4039.

Notes and References

1. Kato . Shinichiro . Shindo . Kazutoshi . Kawai . Hiroyuki . Odagawa . Atsuo . Matsuoka . Michiko . Mochizuki . Junichiro . Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties. . The Journal of Antibiotics . 1993 . 46 . 6 . 892–899 . 10.7164/antibiotics.46.892. 8344870 . free .