Pyrrole-2-carboxylic acid explained

Pyrrole-2-carboxylic acid is an organic compound with the formula HNC4H3CO2H. It is one of two monocarboxylic acids of pyrrole. It is a white solid. It arises in nature by dehydrogenation of the amino acid proline.[1] It also arises by carboxylation of pyrrole.[2] The ethyl ester of this acid is readily prepared from pyrrole.[3]

References

  1. 10.1016/S1074-5521(02)00100-X. Conversion of L-Proline to Pyrrolyl-2-Carboxyl-S-PCP during Undecylprodigiosin and Pyoluteorin Biosynthesis. 2002. Thomas. Michael G.. Burkart. Michael D.. Walsh. Christopher T.. Chemistry & Biology. 9. 2. 171–184. 11880032. free.
  2. 10.1016/S1381-1177(00)00038-2. Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase and its application. 2001. Wieser. Marco. Yoshida. Toyokazu. Nagasawa. Toru. Journal of Molecular Catalysis B: Enzymatic. 11. 4–6. 179–184.
  3. Denis M. Bailey, Robert E. Johnson, and Noel F. Albertson. 10.15227/orgsyn.051.0100. Ethyl Pyrrole-2-Carboxylate. Organic Syntheses. 1971. 51. 100.

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