Pyrazolopyridines Explained

The pyrazolopyridines are a group of drugs investigated as anxiolytics which act as positive allosteric modulators of the GABA_A receptor via the barbiturate binding site.^{[1] [2]} They include the following compounds:

• Cartazolate (SQ-65,396)
• Etazolate (SQ-20,009)
• ICI-190,622
• Tracazolate (ICI-136,753)

See also

• Barbiturates
• Chlormethiazole
• Etomidate
• Loreclezole

Notes and References

1. Book: Annual Reports in Medicinal Chemistry: Volume 16 . Elsevier . Amsterdam . 1981 . 0-12-040516-4 .
2. Book: Progress in Drug Research / Volume 31 (Progress in Drug Research) . Birkhauser . Boston . 1987 . 3-7643-1837-6 .