PyrR binding site explained
| PyrR binding site |
| Symbol: | PyrR |
| Rfam: | RF00515 |
| Rna Type: | Cis-reg |
| Tax Domain: | Bacteria |
The PyrR binding site is an RNA element that is found upstream of a variety of genes involved in pyrimidine biosynthesis and transport.[1]
The RNA structure permits binding of PyrR protein which regulates pyrimidine biosynthesis in Bacillus subtilis. When the protein binds, a downstream terminator hairpin forms, repressing transcription of biosynthesis genes.
Notes and References
- Bonner ER, D'Elia JN, Billips BK, Switzer RL . Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR . Nucleic Acids Research . 29 . 23 . 4851–4865 . December 2001 . 11726695 . 96680 . 10.1093/nar/29.23.4851 .
