| Pyotr Isakov | |
| Fullname: | Pyotr Yefimovich Isakov |
| Birth Date: | 1900 |
| Birth Place: | Nikolskoye, Pokrov Uyezd, Vladimir Governorate, Russian Empire |
| Death Place: | Moscow, USSR |
| Position: | Striker |
| Years1: | 1916—1922 |
| Years2: | 1923—1925 |
| Years3: | 1926—1930 |
| Years4: | 1931 |
| Years5: | 1932—1933 |
| Clubs5: | Dukat Moscow |
| Nationalyears1: | 1924—1925 |
| Nationalteam1: | USSR |
| Nationalcaps1: | 2 |
| Nationalgoals1: | 0 |
| Manageryears1: | 1934 |
| Manageryears2: | 1935—1941 |
| Manageryears3: | 1943—1944 |
| Manageryears4: | 1945 |
| Manageryears5: | 1945—1948 |
| Managerclubs1: | Promkooperatsiya Moscow (assistant) |
| Managerclubs2: | FC Spartak Moscow (assistant) |
| Managerclubs3: | FC Spartak Moscow (assistant) |
| Managerclubs4: | FC Spartak Moscow |
| Managerclubs5: | FC Spartak Moscow (assistant) |
Pyotr Yefimovich Isakov (Russian: Пётр Ефимович Исаков; July 1900 in Nikolskoye, Pokrov Uyezd, Vladimir Governorate – 3 April 1957 in Moscow) was a Soviet football player and manager.
Isakov made his debut for USSR on 16 November 1924 in a friendly against Turkey.