| Pymatuning Creek | |
| Name Other: | Tributary to Shenango River |
| Map Size: | 300 |
| Pushpin Map: | USA Pennsylvania#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Pymatuning Creek mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania Ohio |
| Subdivision Type3: | Counties |
| Subdivision Name3: | Mercer (PA) Ashtabula (OH) Trumbull (OH) |
| Length: | 36.22miles[1] |
| Discharge1 Location: | Shenango River (Shenango River Lake) |
| Discharge1 Avg: | 223.36cuft/s at mouth with Shenango River (Shenango Lake)[2] |
| Source1: | divide between Pymatuning Creek and Grand River[3] |
| Source1 Location: | Leon, Ohio |
| Source1 Coordinates: | 41.6508°N -80.6092°W[4] |
| Source1 Elevation: | 1100feet |
| Mouth: | Shenango River (Shenango Lake) |
| Mouth Location: | Shenango Lake in South Pymatuning Township |
| Mouth Coordinates: | 41.2944°N -80.4572°W |
| Mouth Elevation: | 896feet |
| Progression: | South |
| River System: | Shenango River |
| Basin Population: | 724 (2010) |
| Tributaries Left: | Stratton Creek Booth Run Chestnut Run |
| Tributaries Right: | Clear Creek Sugar Creek Mill Creek |
| Waterbodies: | Shenango Lake |
Pymatuning Creek is a 36.22miles long tributary to Shenango River Lake that rises in Ashtabula County, Ohio and flows south into Shenango Lake in Mercer County, Pennsylvania. Pymatuning Creek forms most of the western side of Shenango Lake. Pymatuning Creek has been designated as a Wild & Scenic River in Ohio.[5]