Pycnoporopepsin Explained
| Pycnoporopepsin |
| Ec Number: | 3.4.23.30 |
| Cas Number: | 77967-78-3 |
Pycnoporopepsin (proteinase Ia, Pycnoporus coccineus aspartic proteinase, Trametes acid proteinase) is an enzyme.[1] [2] [3] This enzyme catalyses the following chemical reaction
Similar to pepsin A, but narrower, cleaving only three bonds in the B chain of insulin: Ala14-Leu, Tyr16-Leu, and Phe24-Phe
This enzyme is isolated from the basidiomycete Pycnoporus sanguineus.
Notes and References
- Acid protease produced by Trametes sanguinea a wood-destroying fungus. Part I. Purification and crystallization of the enzyme . Tomoda K, Shimazono H . Agric. Biol. Chem. . 1964 . 28 . 770–773 . 10.1271/bbb1961.28.770. free .
- Studies on mold proteases. Part II. Substrate specificity of acid protease of Rhizopus chinensis . Tsuru D, Hattori A, Tsuji H, Yamamoto T, Fukumoto J . Agric. Biol. Chem. . 1969 . 33 . 1419–1426 . 10.1080/00021369.1969.10859482.
- Substrate specificity of carboxyl proteinase from Pycnoporus coccineus, a wood-deteriorating fungus . Ichishima E, Kumagai H, Tomoda K . Curr. Microbiol. . 1980 . 3 . 333–337 . 10.1007/bf02601897.
