| Pusy-et-Épenoux | |
| Commune Status: | Commune |
| Coordinates: | 47.6686°N 6.1511°W |
| Insee: | 70429 |
| Postal Code: | 70000 |
| Arrondissement: | Vesoul |
| Canton: | Vesoul-1 |
| Intercommunality: | CA Vesoul |
| Elevation Min M: | 218 |
| Elevation Max M: | 294 |
| Area Km2: | 10.07 |
Pusy-et-Épenoux is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.
The town is located near Vesoul.