Pulmonary hyalinizing granuloma explained

Pulmonary hyalinizing granuloma is a lesional pattern of pulmonary inflammatory pseudotumor.^{[1] [2]}

Pathology

Pulmonary hyalinizing granuloma is characterized by localized changes in lung architecture determined by deposition of hyaline collagenous fibrosis accompanied by sparse lymphocytic infiltrate that compresses and distorts the remaining bronchioles. A higher magnification, the mass is composed by hypocellular collagen lamellae.^[3]

Associations

• Morvan Syndrome
• HIV/AIDS^[4]
• Posterior uveitis^[5]
• Castleman's disease^[6]

Notes and References

1. 20592998. 2010. Brandão. V. Hyalinizing granuloma: An unusual case of a pulmonary mass. Case Reports in Medicine. 2010. 984765. Marchiori. E. Zanetti. G. Abdalla. G. Ventura. N. Constantino. C. L.. Pereira. M. L.. Martins. P. Canellas. R. Muccillo. A. Varella De Oliveira. R. 10.1155/2010/984765. 2892707. free.
2. 21085833. 2010. Arruda. G. D.. Recurrent pulmonary hyalinizing granuloma. Jornal Brasileiro de Pneumologia. 36. 5. 662–5. Carvalho. P. C.. Andrade. M. P.. Cusmanich. M. C.. Bandeira. G. Tozaki. F. S.. 10.1590/s1806-37132010000500019. free.
3. 20592998. 2010. Brandão. V. Hyalinizing granuloma: An unusual case of a pulmonary mass. Case Reports in Medicine. 2010. 984765. Marchiori. E. Zanetti. G. Abdalla. G. Ventura. N. Constantino. C. L.. Pereira. M. L.. Martins. P. Canellas. R. Muccillo. A. Varella De Oliveira. R. 10.1155/2010/984765. 2892707. free.
4. 18923729. 2007. Liu. T. Pulmonary hyalinizing granuloma in HIV/AIDS. The Canadian Journal of Infectious Diseases & Medical Microbiology. 18. 5. 305–7. Kyrollos. M. Kravcik. S. 2533561. 10.1155/2007/208140. free.
5. 15329468. 2004. Esme. H. A case of pulmonary hyalinizing granuloma associated with posterior uveitis. The Tohoku Journal of Experimental Medicine. 204. 1. 93–7. Ermis. S. S.. Fidan. F. Unlu. M. Dilek. F. H. . 10.1620/tjem.204.93. free.
6. 7849383. 1994. Atagi. S. Pulmonary hyalinizing granuloma with Castleman's disease. Internal Medicine. 33. 11. 689–91. Sakatani. M. Akira. M. Yamamoto. S. Ueda. E. 10.2169/internalmedicine.33.689. free.