| Puisieux-et-Clanlieu | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Puisieux-et-Clanlieu (Aisne).svg |
| Arrondissement: | Vervins |
| Canton: | Marle |
| Insee: | 02629 |
| Postal Code: | 02120 |
| Mayor: | Jean Grenier[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Thiérache du Centre |
| Coordinates: | 49.8547°N 3.6783°W |
| Elevation M: | 125 |
| Elevation Min M: | 99 |
| Elevation Max M: | 160 |
| Area Km2: | 17.42 |
Puisieux-et-Clanlieu (in French pronounced as /pɥizjø e klɑ̃ljø/) is a commune in the Aisne department in Hauts-de-France in northern France.