| Puerto Santander | |
| Settlement Type: | Municipality and town |
| Mapsize: | 250px |
| Pushpin Map: | Colombia |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Colombia |
| Subdivision Type: | Country |
| Subdivision Name: |  Colombia |
| Subdivision Type1: | Department |
| Subdivision Name1: | Amazonas Department |
| Coordinates: | -0.6192°N -72.3833°W |
| Timezone: | Colombia Standard Time |
| Utc Offset: | -5 |
| Blank Name: | Climate |
Puerto Santander is a town and municipality in the Colombian Department of Amazonas. The economy relies on fishing, farming and, to a lesser extent, on hunting.