| Official Name: | Puerto San José |
| Settlement Type: | Town |
| Pushpin Map: | Guatemala |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Guatemala |
| Subdivision Type: | Country |
| Subdivision Name: | Guatemala |
| Subdivision Name1: | Escuintla |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | San José |
| Unit Pref: | Imperial |
| Population Total: | 23887 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Coordinates: | 13.9333°N -139°W |
Puerto San José is a town on Guatemala's Pacific Ocean coast, in the department of Escuintla. It has a population of 23,887 (2018 census),[1] making it the largest town along the Pacific coast of Guatemala. It was the Pacific port for Guatemala, but this was superseded in the 20th century by Puerto Quetzal, four kilometres to the east of the town. The Puerto Quetzal complex is the major employer in the town. The local tourist industry caters largely for weekenders from Guatemala City. San José Airport has been refurbished lately and is now the official alternate airport for Guatemala City.
Puerto San José has a tropical savanna climate (Köppen: Aw) with a wet season from May to October, and a dry season from November to April.