| State: | PR |
| Type: | PR |
| Route: | 166 |
| Alternate Name: | Spanish; Castilian: Avenida Jorge Alberto Ramos Comas[1] |
| Length Km: | 2.7 |
| Direction A: | West |
| Terminus A: | in Sabana Grande Abajo–Maresúa |
| Junction: | in San Germán barrio-pueblo |
| Direction B: | East |
| Terminus B: | in Retiro |
| Municipalities: | San Germán |
| Previous Type: | Urban |
| Previous Route: | 165 |
| Next Type: | Urban |
| Next Route: | 167 |
Puerto Rico Highway 166 (PR-166) is a by-pass in San Germán, Puerto Rico. The highway is an avenue which was built for drivers passing through PR-102 could bypass the downtown area of San Germán.[2]
Among its intersections are PR-102 (to downtown San Germán, Cabo Rojo and Sabana Grande), PR-101 (to Lajas) and PR-122 (to PR-2).[3]