| State: | PR |
| Type: | PR |
| Route: | 121 |
| Maint: | Puerto Rico DTPW |
| Length Km: | 15.4 |
| Direction A: | West |
| Terminus A: | in Sabana Grande barrio-pueblo |
| Junction: |
|
| Direction B: | East |
| Terminus B: | in Susúa Baja |
| Municipalities: | Sabana Grande, Yauco |
| Previous Type: | Sec |
| Previous Route: | 120 |
| Next Type: | Sec |
| Next Route: | 122 |
Puerto Rico Highway 121 (PR-121) is a road that travels from Sabana Grande, Puerto Rico to Yauco.[1] This highway begins at its intersection with PR-102 and PR-368 in downtown Sabana Grande and ends at its junction with PR-127 and PR-128 in Susúa Baja.[2]