Publius Cornelius Scipio Nasica (c. 154 – 111 BC) was a politician of the Roman Republic. He belonged to the great patrician family of the Cornelii Scipiones, and was the son of the pontifex maximus Nasica Serapio, who famously murdered Tiberius Gracchus in 133 BC. Nasica was on track to a prestigious career like most of his ancestors, being praetor in 118 BC, but he died during his consulship in 111 BC.
He was the matrilineal great-grandson of Scipio Africanus. He was married to Caecilia Metella, daughter of Quintus Caecilius Metellus Macedonicus. He had two children: Publius Cornelius Scipio Nasica, who married a daughter of the famous orator Lucius Licinius Crassus, and a daughter who married Publius Cornelius Lentulus Marcellinus. His son was praetor in 93 BC and the father of Quintus Caecilius Metellus Pius Scipio Nasica.