Pterocarpin synthase explained

pterocarpin synthase
Ec Number:	1.1.1.246
Cas Number:	118477-70-6
Go Code:	0050229

In enzymology, a pterocarpin synthase is an enzyme that catalyzes the chemical reaction

medicarpin + NADP⁺ + H₂O

\rightleftharpoons vestitone + NADPH + H⁺

The 3 substrates of this enzyme are medicarpin, NADP⁺, and H₂O, whereas its 3 products are vestitone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is medicarpin:NADP⁺ 2'-oxidoreductase. This enzyme is also called pterocarpan synthase. This enzyme participates in isoflavonoid biosynthesis.

References

• Bless W, Barz W . 1988 . Isolation of pterocarpan synthase, the terminal enzyme of pterocarpan phytoalexin biosynthesis in cell-suspension cultures of Cicer arietinum . FEBS Lett. . 235 . 47 - 50 . 10.1016/0014-5793(88)81231-6 . free .