Psoromic acid explained

Psoromic acid is a β-orcinol depsidone with the molecular formula C₁₈H₁₄O₈. Psoromic acid inhibits herpes simplex viruses type 1 and type 2.^[1] Furthermore, it inhibits the RabGGTase.^[2] Psoromic acid occurs in antarctic lichens.^{[1] [3]}

Further reading

• Deraeve . Céline . Guo . Zhong . Bon . Robin S. . Blankenfeldt . Wulf . DiLucrezia . Raffaella . Wolf . Alexander . Menninger . Sascha . Stigter . E. Anouk . Wetzel . Stefan . Choidas . Axel . Alexandrov . Kirill . Waldmann . Herbert . Goody . Roger S. . Wu . Yao-Wen . Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase . Journal of the American Chemical Society . 2 May 2012 . 134 . 17 . 7384–7391 . 10.1021/ja211305j. 22480322 .
• Book: Der Stoffwechsel Sekundärer Pflanzenstoffe / The Metabolism of Secondary Plant Products . 11 November 2013 . Springer Science & Business Media . 978-3-662-26784-4 . 592 . en.
• Book: Year-book of Pharmacy . 1883 . J. & A. Churchill . 246 . en.
• Book: Issues in Chemistry and General Chemical Research: 2013 Edition . 1 May 2013 . ScholarlyEditions . 978-1-4901-0631-1 . 323 . en.

Notes and References

1. Hassan . Sherif T. S. . Šudomová . Miroslava . Berchová-Bímová . Kateřina . Šmejkal . Karel . Echeverría . Javier . Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties . Molecules . 11 August 2019 . 24 . 16 . 2912 . 10.3390/molecules24162912. 31405197 . 6720901 . free .
2. Deraeve . Céline . Guo . Zhong . Bon . Robin S. . Blankenfeldt . Wulf . DiLucrezia . Raffaella . Wolf . Alexander . Menninger . Sascha . Stigter . E. Anouk . Wetzel . Stefan . Choidas . Axel . Alexandrov . Kirill . Waldmann . Herbert . Goody . Roger S. . Wu . Yao-Wen . Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase . Journal of the American Chemical Society . 2 May 2012 . 134 . 17 . 7384–7391 . 10.1021/ja211305j. 22480322 .
3. Book: Sukumaran . Swapna Thacheril . Sugathan . Shiburaj . Abdulhameed . Sabu . Plant Metabolites: Methods, Applications and Prospects . 28 November 2020 . Springer Nature . 978-981-15-5136-9 . 278 . en.