Pseudobaptigenin synthase explained

Pseudobaptigenin synthase
Ec Number:	1.14.21.8

Pseudobaptigenin synthase is an enzyme with systematic name calycosin,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming).^[1] This enzyme catalyses the following chemical reaction

(1) calycosin + NADPH + H⁺ + O₂

\rightleftharpoons pseudobaptigenin + NADP⁺ + 2 H₂O

(2) pratensein + NADPH + H⁺ + O₂

\rightleftharpoons 5-hydroxypseudobaptigenin + NADP+ + 2 H₂O

Pseudobaptigenin synthase is a heme-thiolate enzyme (P450) that catalyses a step in the biosynthesis of (-)-maackiain.

Notes and References

1. Cytochrome P₄₅₀-dependent methylenedioxy bridge formation in Cicer arietinum . Clemens S, Barz W . Phytochemistry . 1996 . 41 . 457–460 . 10.1016/0031-9422(95)00618-4.