| Honorific Prefix: | General |
| Prudencio Ortiz de Rozas | |
| Birth Name: | Prudencio Domingo del Corazón de Jesús Ortiz de Rozas y López de Osornio |
| Birth Date: | 1800 |
| Death Date: | 1857 |
| Spouse: | Catalina Almada Etelvina Romero |
| Occupation: | army landowner merchant |
| Profession: | military man |
| Serviceyears: | c. 1824-1845 |
| Rank: | General |
| Commands: | Regimiento 3° de Milicia Activa de Caballería Regimiento 6° de Milicias de Caballería de Campaña |
| Battles: | Batalla de las Vizcacheras Batalla del Puente de Márquez Batalla de San José de Flores Revolución de los Restauradores Batalla de Chascomús |
| Awards: | is not set --> |
Prudencio Ortiz de Rozas (April 28, 1800 – June 1, 1857) was an Argentine general, brother of governor Juan Manuel de Rosas. He fought at the Battle of Márquez Bridge and San José de Flores, and took part in the agreements of Rosas and Juan Lavalle in Cañuelas and Barracas. He took part in the battle of Chascomús, that defeated the Freemen of the South.