Prosolanapyrone-III cycloisomerase explained
| Prosolanapyrone-III cycloisomerase |
| Ec Number: | 5.5.1.20 |
Prosolanapyrone-III cycloisomerase (Sol5, SPS, solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cyclosiomerase)) is an enzyme with systematic name prosolanapyrone-III:(-)-solanapyrone A isomerase.[1] [2] [3] This enzyme catalyses the following chemical reaction
prosolanapyrone III
(-)-solanapyrone A
The enzyme is involved in the biosynthesis of the phytotoxin solanapyrone in some fungi.
Notes and References
- Kasahara K, Miyamoto T, Fujimoto T, Oguri H, Tokiwano T, Oikawa H, Ebizuka Y, Fujii I . Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani . ChemBioChem . 11 . 9 . 1245–52 . June 2010 . 20486243 . 10.1002/cbic.201000173 .
- Katayama K, Kobayashi T, Oikawa H, Honma M, Ichihara A . Enzymatic activity and partial purification of solanapyrone synthase: first enzyme catalyzing Diels-Alder reaction . Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology . 1384 . 2 . 387–95 . May 1998 . 9659400 . 10.1016/s0167-4838(98)00040-5 .
- Katayama K, Kobayashi T, Chijimatsu M, Ichihara A, Oikawa H . Purification and N-terminal amino acid sequence of solanapyrone synthase, a natural Diels-Alderase from Alternaria solani . Bioscience, Biotechnology, and Biochemistry . 72 . 2 . 604–7 . February 2008 . 18256508 . 10.1271/bbb.70600 . free .
