| Propionate—CoA ligase | |
| Ec Number: | 6.2.1.17 |
| Cas Number: | 55326-49-3 |
| Go Code: | 0050218 |
In enzymology, a propionate—CoA ligase is an enzyme that catalyzes the chemical reaction
ATP + propanoate + CoA
\rightleftharpoons
The 3 substrates of this enzyme are ATP, propanoate, and CoA, whereas its 3 products are AMP, diphosphate, and propanoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is propanoate:CoA ligase (AMP-forming). This enzyme is also called propionyl-CoA synthetase. This enzyme participates in propanoate metabolism.