Propamidine Explained

Propamidine is an antiseptic and disinfectant.

Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.[1]

Propamidine is a member of the aromatic diamidine group of compounds which possess bacteriostatic properties against a wide range of organisms. These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some Gram-negative bacilli, the activity of the diamidines being retained in the presence of organic matter such as tissue fluids, pus and serum.[2]

Notes and References

  1. Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M . Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga . Antimicrob. Agents Chemother. . 39 . 2 . 339–42 . February 1995 . 7726493 . 162538 . 10.1128/aac.39.2.339.
  2. Web site: Brolene Eye Drops - Summary of Product Characteristics (SmPC) - (eMC). www.medicines.org.uk. en. 2018-11-23.