| Province: | PE |
| Type: | PE |
| Route: | 12 |
| Maint: | the Department of Transportation, Infrastructure, and Energy |
| Length Km: | 112 |
| Length Ref: | [1] |
| Direction A: | South |
| Terminus A: | in Miscouche |
| Junction: | |
| Direction B: | North |
| Terminus B: | North Cape Hiking Trail in Tignish |
| Counties: | Prince |
| Previous Type: | PE |
| Previous Route: | 11 |
| Next Type: | PE |
| Next Route: | 13 |
Route 12 is a 112km (70miles), two-lane, uncontrolled-access, secondary highway in western Prince Edward Island, Canada. Its southern terminus is at Route 11 in Miscouche and its northern terminus is at the North Cape Hiking Trail in Tignish. The route parallels Route 2 as it travels toward the North Cape.
The route begins at its southern terminus, goes north, and turns left near Rosehill. It crosses the Grand River and turns right in the community of the same name. It continues north and turns left in Low Point. Two left turns in Foxley River lead to a 2.7km (01.7miles) concurrency with Route 2 between Portage and West Devon. Two bridges over the Trout and Mill rivers lead to a right turn into Alberton. Travelling further north up the north coast of the island, the route crosses the Kildare River and goes by Tignish before ending at the North Cape Hiking Trail.
| County | Location | km | mi | Junction | Notes |
|---|---|---|---|---|---|
| Prince County | Miscouche | 0 | 0 | Southern terminus of route | |
| 1.5 | 0.9 | ||||
| Rosehill | 5.7 | 3.5 | |||
| 8.2 | 5.1 | ||||
| 14.1 | 8.8 | ||||
| Grand River | 19.0 | 11.8 | Southern terminus of concurrency with Route 131 | ||
| 19.6 | 12.2 | Northern terminus of concurrency with Route 131 | |||
| Birch Hill | 26.6 | 16.5 | |||
| 29.0 | 18.0 | ||||
| Tyne Valley | 34.8 | 21.6 | |||
| Ellerslie-Bideford | 38.4 | 23.9 | |||
| 40.5 | 25.2 | ||||
| 41.8 | 26.0 | ||||
| Freeland | 46.7 | 29.0 | |||
| 47.0 | 29.2 | ||||
| Foxley River | 50.6 | 31.4 | |||
| Portage | 56.0 | 34.8 | Southern terminus of concurrency with Route 2 | ||
| 58.7 | 36.5 | Northern terminus of concurrency with Route 2 | |||
| Coleman | 62.8 | 39.0 | |||
| O'Leary | 64.8 | 40.3 | |||
| Cascumpec | 68.7 | 42.7 | |||
| 70.7 | 43.9 | ||||
| Alberton | 76.9 | 47.8 | |||
| 77.3 | 48.0 | ||||
| 78.7 | 48.9 | ||||
| 87.3 | 54.2 | ||||
| Tignish | 87.9 | 54.6 | |||
| 99.2 | 61.6 | ||||
| 105 | 65.2 | ||||
| 108 | 67.1 | ||||
| 112 | 69.6 | North Cape Hiking Trail | Northern terminus of route |