| Competition: | Primera División de México |
| Season: | 2004–05 |
| Winners: | América (10th title) |
| Relegated: | Puebla |
| Continentalcup1: | Champions' Cup |
| Continentalcup1 Qualifiers: | América |
| Continentalcup2: | Interliga |
| Continentalcup2 Qualifiers: | UANL Guadalajara Atlante Santos Laguna Chiapas Toluca América Necaxa |
| Continentalcup3: | Copa Sudamericana |
| Continentalcup3 Qualifiers: | América |
| League Topscorer: | Vicente Matías Vuoso (15 goals) |
| Prevseason: | Apertura 2004 |
| Nextseason: | Apertura 2005 |
Primera División de México (Mexican First Division) Clausura 2005 was the 2005 edition of Primera División de México, crowning Mexico's spring champion in football. América won the championship for the tenth time in its history and thus qualified for the CONCACAF Champions' Cup 2006.[1]
Players sorted first by goals scored, then by last name. Only regular season goals listed.
| Rank | Player | Club | Goals | ||
|---|---|---|---|---|---|
| align=center rowspan=1 | 1 |  Vicente Matías Vuoso | Santos Laguna | align=center rowspan=1 | 15 |
| align=center rowspan=2 | 2 |  Kléber Boas | América | align=center rowspan=2 | 12 |
 Omar Bravo | Guadalajara | ||||
| align=center rowspan=3 | 4 | Gustavo Biscayzacú | Veracruz | align=center rowspan=3 | 10 |
| Walter Gaitán | UANL | ||||
| Sebastián González | Atlante | ||||
| align=center rowspan=3 | 7 | Claudio López | América | align=center rowspan=3 | 9 |
| Daniel Ludueña | UAG | ||||
| Eliomar Marcón | UAG | ||||
| align=center rowspan=6 | 10 | Jared Borgetti | Pachuca | align=center rowspan=6 | 8 |
| Salvador Cabañas | Chiapas | ||||
| Carlos Casartelli | Monterrey | ||||
| César Delgado | Cruz Azul | ||||
| Francisco Fonseca | Cruz Azul | ||||
| Alfredo Moreno | Necaxa |
Source: MedioTiempo
3–3 on aggregate. Cruz Azul advanced for being the higher seeded team.----
3–3 on aggregate. América advanced for being the higher seeded team.----
4–4 on aggregate. Morelia advanced for being the higher seeded team.----
Tecos won 4–1 on aggregate.----
América won 6–2 on aggregate.----
UAG won 2–1 on aggregate.
América won 7–4 on aggregate.
| Pos. | Team | Pts. | Pld. | Ave. | |
|---|---|---|---|---|---|
| 14. | Atlas | 142 | 110 | 1.2909 | |
| 15. | Chiapas | 138 | 110 | 1.2545 | |
| 16. | Sinaloa | 42 | 34 | 1.2352 | |
| 17. | UAG | 130 | 110 | 1.1818 | |
| 18. | Puebla | 115 | 110 | 1.0454 |