| Competition: | Primera División de México |
| Season: | 1981–82 |
| Winners: | UANL (2nd title) |
| Relegated: | Tampico Madero |
| Continentalcup1: | Champions' Cup |
| Matches: | 394 |
| Total Goals: | 1022 |
| Prevseason: | 1980–81 |
| Nextseason: | 1982–83 |
Statistics of Primera División de México for the 1981–82 season.
It was contested by 20 teams, and UANL won the championship.
Atlético Morelia was promoted from Segunda División.
After the season, the owner of Atlético Español decided to sell the team to the Mexican league. This gave way for Necaxa to come back to play in the 1982-83 season.
Tampico was relegated to Segunda División, however, the oil workers' syndicate acquired the Atletas Campesinos franchise and created a new team called Tampico Madero.
Atlas won 4-2 on aggregate. Tampico was relegated to Segunda División.
U.A.N.L. won the championship.
Atlante won 5-3 on aggregate.----
Deportivo Neza won 2-3 on aggregate.----
América won 5-3 on aggregate.----
UANL won 3-2 on aggregate.
Atlante won 1-0 on aggregate.----
UANL won 1-2 on aggregate.
Aggregate tied. UANL won 1-3 on penalty shootout.
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