| Competition: | Primera División |
| Season: | 1943 |
| Winners: | Boca Juniors (11th title) |
| Promoted: | Rosario Central |
| Relegated: | Gimnasia y Esgrima (LP) |
| League Topscorer: |  Luis Arrieta Angel Labruna Raúl Frutos (23 goals each) |
| Prevseason: | 1942 |
| Nextseason: | 1944 |
The 1943 Argentine Primera División was the 52nd season of top-flight football in Argentina. The season began on April 18 and ended on December 5.[1]
Boca Juniors won its 11th league title while Gimnasia y Esgrima (LP) was relegated.