Prime Brook is a community in the Canadian province of Nova Scotia, located in the Cape Breton Regional Municipality on Cape Breton Island.
In the 2021 Census of Population conducted by Statistics Canada, Prime Brook had a population of 186 living in 84 of its 92 total private dwellings, a change of from its 2016 population of 183. With a land area of, it had a population density of in 2021.[1]