| 22nd Lo Nuestro Awards | |
| Country: | United States |
| Location: | American Airlines Arena, Miami, FL |
| Network: | Univision |
| Date: | February 18, 2010 |
| Host: | Ana Bárbara and Víctor Manuelle |
| Previous: | 21st |
| Next: | 23rd |
Premio Lo Nuestro 2010 was held on Thursday February 18, 2010 at the American Airlines Arena in Miami, FL was broadcast live on the Univision Network. The nominees were announced in December 2009 during a live televised morning show Despierta América! on Univision Network. This year marked the first time the awards are presented in High Definition.[1]
| Medley (Opening Act) — 03:54 | ||
| Medley (Opening Act) — 04:59 | ||
| Estuve (Opening Act) — 03:06 | ||
| Descontrol | ||
| Me Gusta Todo de Tí | ||
| Quédate | ||
| Mi Princesa | ||
| Ya Lo Sé | ||
| Ni Rosas Ni Juguetes | ||
| Te Pido Perdón | ||
| Alejandro Fernández | Se Me Va la Voz (Special Performing: Career Achievement Award) — 06:39 | |
| Su Veneno & Dile al Amor | ||
| Lo Intentamos | ||
| Me Enamore De Ti (Special Performing: Lifetime Achievement Award) | ||
| Tu Ultima Parada & Rata de dos Patas — 04:56 | ||
| Yo No Sé Mañana | ||
| Por Amarte Así | ||
| Manos al Aire | ||
| Jorge Celedón, Hector "El Torito" Acosta & Jimmy Zambrano | Sin Perdon | |
| Maria Lola |
| Categorie | Winner | Nominees | |
|---|---|---|---|
| Premio Lo Nuestro Artist of the Year | |||
| Collaboration of the Year | Luis Fonsi featuring Aleks Syntek, David Bisbal and Noel Schajris - "Aquí Estoy Yo" |
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