| Preiļupe | |
| Source1: | Salmejs Lake |
| Source1 Coordinates: | 56.2914°N 26.8661°W |
| Mouth: | Feimanka |
| Mouth Coordinates: | 56.2826°N 26.635°W |
| Progression: | Feimanka→ |
| Subdivision Type1: | Country |
| Subdivision Name1: | Latvia |
| Length: | 19km (12miles) |
The Preiļupe (pl|Prelka) is a stream in Latvia (Latgale) in Riebinu, Preiļu and Vārkava counties. It is long and is a left tributary of the river Feimanka. Its source is Salmejs Lake, from which it flows westward, through the city of Preili, and then into the Feimanka in the area of Škilteri. Its estimated terrain elevation is 124 metres above sea level.