Pregna-4,20-dien-3,6-dione explained

Pregnadienedione (PDD), or pregna-4,20-dien-3,6-dione, is a steroid and pherine, or synthetic pheromone.^{[1] [2]} PDD has been found to activate the vomeronasal organ in men. Moreover, inhalation by men has been found to affect autonomic and central function and to lower luteinizing hormone and testosterone levels, while inhalation by women has few or no effects.

See also

• List of neurosteroids § Pheromones and pherines

Further reading

• Monti-Bloch L, Diaz-Sanchez V, Jennings-White C, Berliner DL . Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione . The Journal of Steroid Biochemistry and Molecular Biology . 65 . 1–6 . 237–42 . April 1998 . 9699878 . 10.1016/s0960-0760(98)00025-9 .

Notes and References

1. Hayes W . Human pheromones: have they been demonstrated? . Behavioral Ecology and Sociobiology . 54 . 2 . 89–97 . 2003 . 10.1007/s00265-003-0613-4 . 37400635 .
2. Monti-Bloch L, Diaz-Sanchez V, Jennings-White C, Berliner DL . Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione . The Journal of Steroid Biochemistry and Molecular Biology . 65 . 1–6 . 237–242 . April 1998 . 9699878 . 10.1016/S0960-0760(98)00025-9 . 32805290 .