| Preah Sdach | |
| Native Name: | Central Khmer: ព្រះស្ដេច |
| Official Name: | Preah Sdach District Central Khmer: ស្រុកព្រះស្ដេច |
| Settlement Type: | District |
| Pushpin Map: | Cambodia |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Cambodia |
| Subdivision Type: | Country |
| Subdivision Name: |  Cambodia |
| Subdivision Type1: | Province |
| Subdivision Name1: | Prey Veng |
| Population As Of: | 1998 |
| Population Footnotes: | [1] |
| Population Total: | 106,459 |
| Timezone: | ICT |
| Utc Offset: | +7 |
| Coordinates: | 11.0833°N 126°W |
| Geocode: | 1409 |
Preah Sdach (Central Khmer: ព្រះស្ដេច, in Central Khmer pronounced as /prĕəh sɗac/; "Sacred Prince") is a district located in Prey Veng Province, in south eastern Cambodia. The most popular market of Preah Sdach District is Phsar Trea which is located in Trea Commune. The Japanese-Cambodian Friendship High School is also in this district.