| Poul-Erik Thygesen | |
| Birth Date: | 1950 7, df=yes |
| Birth Place: | Gentofte, Denmark |
| Position: | Forward |
| Years1: | 1968–1973 |
| Clubs1: | B 1903 |
| Years2: | 1973–1975 |
| Clubs2: | Werder Bremen |
| Caps2: | 20 |
| Goals2: | 4 |
| Years3: | 1975–1977 |
| Clubs3: | FC Winterthur |
| Years4: | 1977–1978 |
| Clubs4: | Glostrup IC |
| Years5: | 1979–1980 |
| Clubs5: | B 1903 |
Poul-Erik Thygesen (born 17 July 1950) is a Danish former professional footballer who played as a forward.