Possum Trot Creek is a stream in Crawford and Iron counties in the U.S. state of Missouri. It is a tributary of Huzzah Creek.
The stream headwaters arise in the northwest corner of Iron County just northwest of Viburnum (at 37.7214°N -91.1383°W) and the stream flows northwest to its confluence with Huzzah Creek in Crawford County (at 37.7656°N -91.1736°W).[1] Mill Rock Creek enters the Huzzah just downstream from Possum Trot Creek.[1]
Possum Trot Creek, also called Possum Creek, was named for the fact it was a favorite hunting ground of opossums by early settlers.[2]