| Porcupine River | |
| Pushpin Map: | Canada Ontario |
| Pushpin Map Caption: | Location of the mouth of the Porcupine River in Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Region |
| Subdivision Name3: | Northeastern Ontario |
| Subdivision Type4: | District |
| Subdivision Name4: | Cochrane |
| Length: | 32km (20miles) |
| Source1: | Porcupine Lake |
| Source1 Coordinates: | 48.4947°N -81.175°W |
| Source1 Elevation: | 277m (909feet) |
| Mouth: | Night Hawk Lake |
| Mouth Coordinates: | 48.5239°N -81.0172°W |
| Mouth Elevation: | 274m (899feet) |
The Porcupine River is a river in the James Bay and Moose River drainage basins in the city of Timmins, Cochrane District in northeastern Ontario, Canada. It flows 32km (20miles) from Porcupine Lake to its mouth at Night Hawk Lake, the source of the Frederick House River, a tributary of the Abitibi River.
The Porcupine River begins at Porcupine Lake at an elevation of 277m (909feet) and flows northeast under Highway 101 out of the lake at the community of Porcupine between the neighbourhoods of Pottsville and Golden City. It flows northeast, takes in the left tributary North Porcupine River, flows southeast through the neighbourhood of Hoyle and again under Highway 101, and reaches its mouth at the northwest of Night Hawk Lake at an elevation of 274m (899feet).
The Timmins/Porcupine Lake Water Aerodrome is on Porcupine Lake.