| Popoloca | |
| Region: | Puebla, Mexico |
| Date: | 2020 census |
| Ref: | [1] |
| Familycolor: | American |
| Fam1: | Oto-Manguean |
| Fam2: | Popolocan |
| Fam3: | Chocho–Popoloca |
| Glotto: | popo1294 |
| Glottorefname: | Popolocan |
| Child1: | Eastern |
| Child2: | Central/Western |
| Map: | Otomanguean Languages.png |
| Mapcaption: | The Popoloca languages, number 6 (purple), center. |
Popoloca is an indigenous Mexican cluster of languages of the Popolocan branch of the Oto-Manguean language family, closely related to Mazatec. They are spoken by 17,000 people[1] in Puebla state, Mexico, near Tehuacán.
The Ethnologue distinguishes seven varieties of Popoloca as separate languages. However, these fall into four groups with 75% mutual intelligibility or greater.