| Polykastano | |
| Name Local: | Πολυκάστανο |
| Type: | community |
| Periph: | Western Macedonia |
| Periphunit: | Kozani |
| Municipality: | Voio |
| Municunit: | Tsotyli |
| Population: | 64 |
| Population As Of: | 2021 |
| Elevation: | 1050 |
| Coordinates: | 40.2938°N 29.269°W |
| Postal Code: | 500 02 |
| Area Code: | +30-2468 |
| Licence: | ΚΖ |
Polykastano (el|Πολυκάστανο, before 1927: Κλεπίστιον – Klepistion),[1] is a village and a community of the Voio municipality.[2] Before the 2011 local government reform it was part of the municipality of Tsotyli, of which it was a municipal district.[2] The 2021 census recorded 64 inhabitants in the village. According to the statistics of Vasil Kanchov ("Macedonia, Ethnography and Statistics"), 250 Greek Christians lived in the village in 1900.[3]