Polyarthritis Explained

Polyarthritis
Field:Rheumatology

Polyarthritis is any type of arthritis that involves 5 or more joints simultaneously. It can be associated with autoimmune conditions; it may be experienced at any age and is not sex specific.[1]

Causes

Polyarthritis is often caused by an auto-immune disorder such as rheumatoid arthritis, psoriatic arthritis, and lupus erythematosus, or other inflammatory rheumatic diseases, like crystal arthropathies. It can also be caused by cancer or various medications.

Another cause of polyarthritis is infection, which may be viral or bacterial. Viruses that cause polyarthritis include alphaviruses, such as chikungunya virus, Sindbis virus and Ross River virus.[2] Arthritis caused by bacterial infection of the joint is termed septic arthritis and does not commonly affect multiple joints. It may notably be caused by gonococcus. Bacteria can also cause polyarthritis not by directly infecting the joints; instead, infection located elsewhere in the body can cause immune reaction, which becomes the direct cause of the inflammation of joints. This form or arthritis is called reactive and often coexists with inflammation of the urethra, and of the conjuctiva in the eye.[3]

See also

Notes and References

  1. Alpay-Kanıtez . N . Çelik . S . Bes . C . Polyarthritis and its differential diagnosis . European Journal of Rheumatology . October 2019 . 6 . 4 . 167–173 . 10.5152/eurjrheum.2019.19145 . 31657698 . 6812894 .
  2. Kafai . NM . Diamond . MS . Fox . JM . Distinct Cellular Tropism and Immune Responses to Alphavirus Infection . Annual Review of Immunology . April 2022 . 40 . 615–649 . 10.1146/annurev-immunol-101220-014952 . 35134315 . 10350340 .
  3. Kumar . A . How to investigate new-onset polyarthritis . Best Practice & Research Clinical Rheumatology . December 2014 . 28 . 6 . 844–859 . 10.1016/j.berh.2015.04.014 . 26096089 . 10 February 2024.