| Image Coa: | DEU Pleisweiler-Oberhofen COA.svg |
| Coordinates: | 49.1183°N 8.0067°W |
| Image Plan: | Pleisweiler-Oberhofen in SÜW.svg |
| State: | Rheinland-Pfalz |
| District: | Südliche Weinstraße |
| Verbandsgemeinde: | Bad Bergzabern |
| Elevation: | 190 |
| Area: | 5.05 |
| Postal Code: | 76889 |
| Area Code: | 06343 |
| Licence: | SÜW |
| Gemeindeschlüssel: | 07 3 37 062 |
| Divisions: | 2 |
| Website: | www.pleisweiler-oberhofen.de |
| Mayor: | Roland Gruschinski[1] |
| Leader Term: | 2019 - 24 |
Pleisweiler-Oberhofen is a municipality in Südliche Weinstraße district, in Rhineland-Palatinate, western Germany.