| Pleasant Hope High School | |
| Streetaddress: | 100 West Cowden Street |
| City: | Pleasant Hope |
| State: | Missouri |
| County: | (Polk County) |
| Zipcode: | 65725 |
| Country: | USA |
| Coordinates: | 37.4644°N -93.2736°W |
| Principal: | James Fox |
| Staff: | 17.22 (FTE) |
| Ratio: | 16.38 |
| Type: | Public high school |
| Enrollment: | 282[1] |
| Enrollment As Of: | 2022-23 |
| Campus: | (Urban/Country)--> |
| Colors: | Black and gold [2] |
| Mascot: | Pirates |
| Superintendent: | Shaundra Ingram |
| Accreditation: | Missouri Department of Elementary and Secondary Education |
| Conference: | Greater Ozarks Conference |
Pleasant Hope High School is a public high school located in Pleasant Hope, Missouri, USA, a small town about 23 miles north of Springfield, Missouri. The school has roughly 250 students, and is the only high school in the Pleasant Hope R-6 School District, which also provides on-site high school educational services to Good Samaritan Boys Ranch, a residential treatment center in nearby Brighton.