| Pleasant Brook | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Pleasant Brook |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Otsego |
| Source1: | Plank Pond |
| Source1 Coordinates: | 42.6976°N -74.6826°W |
| Source1 Elevation: | NaNid = 960673 |
| Mouth: | Cherry Valley Creek |
| Mouth Coordinates: | 42.7187°N -74.7882°W[1] |
| Mouth Elevation: | 1237feet |
| Tributaries Right: | Snyder Creek |
Pleasant Brook is a river in Otsego County, New York. It converges with Cherry Valley Creek west of Pleasant Brook.